Meta-Fexofenadine-d6
Meta-Fexofenadine-d6 is the deuterium labeled meta-Fexofenadine. meta-Fexofenadine (meta-MDL-16455) is an impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti-allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial.
For research use only. We do not sell to patients.
- Formula: C32H33D6NO4
- Molecular Weight:507.69
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
Unlabeled Cas 479035-75-1
-
Molecular Weight 507.69
-
Formula C32H33D6NO4
-
SMILES
O=C(O)C(C([2H])([2H])[2H])(C1=CC(C(O)CCCN2CCC(CC2)C(C3=CC=CC=C3)(O)C4=CC=CC=C4)=CC=C1)C([2H])([2H])[2H]
-
Synonyms
meta-MDL-16455-d6; meta-Terfenadine carboxylate-d6
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Maher HM, et al. Development of validated stability-indicating chromatographic method for the determination of fexofenadine hydrochloride and its related impurities in pharmaceutical tablets. Chem Cent J. 2011 Dec 3;5(1):76. [Content Brief]
[3]. Watanabe N, et al. The effects of fexofenadine on eosinophilia and systemic anaphylaxis in mice infected with Trichinella spiralis. Int Immunopharmacol. 2004 Mar;4(3):367-75. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Meta-Fexofenadine-d6 Related Classifications
HY-100657S Related Classifications
Powered by Bioz