1. Metabolic Enzyme/Protease
    Autophagy
    Apoptosis
    Immunology/Inflammation
    Anti-infection
  2. Phosphatase
    FKBP
    Bacterial
    Autophagy
    Antibiotic
  3. Tacrolimus-13C,d2

Tacrolimus-13C,d2 (Synonyms: FK506-13C,d2; Fujimycin-13C,d2; FR900506-13C,d2)

Cat. No.: HY-13756S
Handling Instructions

Tacrolimus-13C,D2 (FK506-13C,D2) is a 13C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties.

For research use only. We do not sell to patients.

Tacrolimus-13C,d2 Chemical Structure

Tacrolimus-13C,d2 Chemical Structure

CAS No. : 1356841-89-8

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Description

Tacrolimus-13C,D2 (FK506-13C,D2) is a 13C-labeled and deuterium labeled Tacrolimus. Tacrolimus (FK506), a macrocyclic lactone, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, which inhibits T-lymphocyte signal transduction and IL-2 transcription. Immunosuppressive properties[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

807.02

Formula

C4313CH67D2NO12

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Tacrolimus-13C,d2
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