2. Others Metabolic Enzyme/Protease
  3. Liposome Isotope-Labeled Compounds
  4. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70  (Synonyms: 1,2-Distearoyl-sn-glycero-3-PC-d70; DSPC-d70)

Cat. No.: HY-W040193S Purity: ≥99.0%
COA Handling Instructions

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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

For research use only. We do not sell to patients.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d<sub>70</sub> Chemical Structure

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 Chemical Structure

CAS No. : 56952-01-3

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5 mg USD 185 In-stock
10 mg USD 295 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70:

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 Related Antibodies

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Description

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 is the deuterium labeled 1,2-Distearoyl-sn-glycero-3-phosphorylcholine. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine (1,2-Distearoyl-sn-glycero-3-PC; DSPC) is a cylindrical-shaped lipid. 1,2-Distearoyl-sn-glycero-3-phosphorylcholine is used to synthesize liposomes, and is the lipid component in the lipid nanoparticle (LNP) system[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 Related Antibodies
Molecular Weight

860.58

Formula

C44H18D70NO8P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O[C@H](COC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COP(OCC[N+](C)(C)C)([O-])=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : ≥ 30 mg/mL (34.86 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1620 mL 5.8100 mL 11.6201 mL
5 mM 0.2324 mL 1.1620 mL 2.3240 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (248 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 1.1620 mL 5.8100 mL 11.6201 mL 29.0502 mL
5 mM 0.2324 mL 1.1620 mL 2.3240 mL 5.8100 mL
10 mM 0.1162 mL 0.5810 mL 1.1620 mL 2.9050 mL
15 mM 0.0775 mL 0.3873 mL 0.7747 mL 1.9367 mL
20 mM 0.0581 mL 0.2905 mL 0.5810 mL 1.4525 mL
25 mM 0.0465 mL 0.2324 mL 0.4648 mL 1.1620 mL
30 mM 0.0387 mL 0.1937 mL 0.3873 mL 0.9683 mL
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1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d70 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,2-Distearoyl-sn-glycero-3-phosphorylcholine-d7056952-01-31,2-Distearoyl-sn-glycero-3-PC-d70DSPC-d70LiposomeIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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