N-Nitrosodiethylamine-d10
Based on 1 Customer Validation
N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 1219794-54-3
- Formula: C4D10N2O
- Molecular Weight:112.20
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1219794-54-3
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Unlabeled Cas 55-18-5
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Appearance Liquid
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Molecular Weight 112.20
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Formula C4D10N2O
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Color Colorless to light yellow
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SMILES
[2H]C([2H])([2H])C([2H])([2H])N(N=O)C([2H])([2H])C([2H])([2H])[2H]
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Synonyms
Diethylnitrosamine-d10; DEN-d10; DENA-d10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : ≥ 100 mg/mL (891.27 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.9127 mL | 44.5633 mL | 89.1266 mL | 222.8164 mL |
| 5 mM | 1.7825 mL | 8.9127 mL | 17.8253 mL | 44.5633 mL | |
| 10 mM | 0.8913 mL | 4.4563 mL | 8.9127 mL | 22.2816 mL | |
| 15 mM | 0.5942 mL | 2.9709 mL | 5.9418 mL | 14.8544 mL | |
| 20 mM | 0.4456 mL | 2.2282 mL | 4.4563 mL | 11.1408 mL | |
| 25 mM | 0.3565 mL | 1.7825 mL | 3.5651 mL | 8.9127 mL | |
| 30 mM | 0.2971 mL | 1.4854 mL | 2.9709 mL | 7.4272 mL | |
| 40 mM | 0.2228 mL | 1.1141 mL | 2.2282 mL | 5.5704 mL | |
| 50 mM | 0.1783 mL | 0.8913 mL | 1.7825 mL | 4.4563 mL | |
| 60 mM | 0.1485 mL | 0.7427 mL | 1.4854 mL | 3.7136 mL | |
| 80 mM | 0.1114 mL | 0.5570 mL | 1.1141 mL | 2.7852 mL | |
| 100 mM | 0.0891 mL | 0.4456 mL | 0.8913 mL | 2.2282 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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