1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. N-Nitrosodiethylamine

N-Nitrosodiethylamine 

Cat. No.: HY-N7434 Purity: 99.97%
Handling Instructions

N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

For research use only. We do not sell to patients.

N-Nitrosodiethylamine Chemical Structure

N-Nitrosodiethylamine Chemical Structure

CAS No. : 55-18-5

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Estimated Time of Arrival: December 31
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Description

N-Nitrosodiethylamine is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

Molecular Weight

102.14

Formula

C₄H₁₀N₂O

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (979.05 mM; Need ultrasonic)

H2O : 100 mg/mL (979.05 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 9.7905 mL 48.9524 mL 97.9048 mL
5 mM 1.9581 mL 9.7905 mL 19.5810 mL
10 mM 0.9790 mL 4.8952 mL 9.7905 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (24.48 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (24.48 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (24.48 mM); Clear solution

*All of the co-solvents are provided by MCE.
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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
N-Nitrosodiethylamine
Cat. No.:
HY-N7434
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