N-Nitrosodiethylamine (Standard)
Based on 1 Customer Validation
N-Nitrosodiethylamine (Standard) is the analytical standard of N-Nitrosodiethylamine. This product is intended for research and analytical applications. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 55-18-5
- Formula: C4H10N2O
- Molecular Weight:102.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Purity & Documentation
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 55-18-5
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Appearance Liquid
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Molecular Weight 102.14
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Formula C4H10N2O
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Color Colorless to light yellow
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SMILES
CCN(CC)N=O
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Synonyms
Diethylnitrosamine (Standard); DEN (Standard); DENA (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (790 KB)
- English - EN (790 KB)
- Français - FR (790 KB)
- Deutsch - DE (790 KB)
- Norwegian - NO (790 KB)
- Español - ES (790 KB)
- Swedish - SV (790 KB)
- Italian - IT (790 KB)
- Korean - KR (790 KB)
- Portuguese - PT (790 KB)
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Handling Instructions (2659 KB)
References
[1]. Ramakrishnan G, et al. Suppression of N-nitrosodiethylamine induced hepatocarcinogenesis by silymarin in rats. Chem Biol Interact. 2006 Jun 10;161(2):104-14. [Content Brief]
[2]. Bansal AK, et al. Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver. Chem Biol Interact. 2005 Oct 20;156(2-3):101-11. [Content Brief]
[3]. Gombar CT, et al. Pharmacokinetics of N-nitrosodimethylamine in beagles. Cancer Res. 1987 Jan 15;47(2):343-7. [Content Brief]
[4]. Verna L, et al. N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. Pharmacol Ther. 1996;71(1-2):57-81. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
N-Nitrosodiethylamine (Standard) Related Classifications
HY-N7434R Related Classifications
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