Lansoprazole-d4
Based on 1 Customer Validation
Lansoprazole-d4 (AG-1749-d4) is a deuterium labeled Lansoprazole. Lansoprazole is a proton pump inhibitor which prevents the stomach from producing acid.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 934294-22-1
- Formula: C16H10D4F3N3O2S
- Molecular Weight:373.39
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Proton Pump Inhibitor
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 934294-22-1
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Unlabeled Cas 103577-45-3
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Appearance Solid
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Molecular Weight 373.39
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Formula C16H10D4F3N3O2S
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Color Off-white to light yellow
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SMILES
O=S(C1=NC2=C([2H])C([2H])=C([2H])C([2H])=C2N1)CC3=NC=CC(OCC(F)(F)F)=C3C
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Synonyms
AG-1749-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMF : ≥ 30 mg/mL (80.34 mM)
DMSO : ≥ 30 mg/mL (80.34 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 5 mg/mL (13.39 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMF / DMSO | 1 mM | 2.6782 mL | 13.3908 mL | 26.7816 mL | 66.9541 mL |
| 5 mM | 0.5356 mL | 2.6782 mL | 5.3563 mL | 13.3908 mL | |
| 10 mM | 0.2678 mL | 1.3391 mL | 2.6782 mL | 6.6954 mL | |
| DMF / DMSO | 15 mM | 0.1785 mL | 0.8927 mL | 1.7854 mL | 4.4636 mL |
| 20 mM | 0.1339 mL | 0.6695 mL | 1.3391 mL | 3.3477 mL | |
| 25 mM | 0.1071 mL | 0.5356 mL | 1.0713 mL | 2.6782 mL | |
| 30 mM | 0.0893 mL | 0.4464 mL | 0.8927 mL | 2.2318 mL | |
| 40 mM | 0.0670 mL | 0.3348 mL | 0.6695 mL | 1.6739 mL | |
| 50 mM | 0.0536 mL | 0.2678 mL | 0.5356 mL | 1.3391 mL | |
| 60 mM | 0.0446 mL | 0.2232 mL | 0.4464 mL | 1.1159 mL | |
| 80 mM | 0.0335 mL | 0.1674 mL | 0.3348 mL | 0.8369 mL |