1. GPCR/G Protein
  2. Adenosine Receptor
  3. Istradefylline-13C,d3

Istradefylline-13C,d3 (Synonyms: KW-6002-13C,d3)

Cat. No.: HY-10888S
Handling Instructions

Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.

For research use only. We do not sell to patients.

Istradefylline-13C,d3 Chemical Structure

Istradefylline-13C,d3 Chemical Structure

CAS No. : 2749234-46-4

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Description

Istradefylline-13C,d3 is the 13C- and deuterium labeled Istradefylline. Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[86].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

388.44

Formula

C1913CH21D3N4O4

CAS No.
SMILES

O=C(N1CC)N(CC)C2=C(N([13C]([2H])([2H])[2H])C(/C=C/C3=CC=C(OC)C(OC)=C3)=N2)C1=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Istradefylline-13C,d3
Cat. No.:
HY-10888S
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