Hypoxanthine-15N4
Based on 2 publication(s) in Google Scholar
Hypoxanthine-15N4 is the 15N labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
For research use only. We do not sell to patients.
- Purity: 98.5%
- CAS No.: 77910-30-6
- Formula: C5H415N4O
- Molecular Weight:140.09
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Hypoxanthine-15N4
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 77910-30-6
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Unlabeled Cas 68-94-0
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Appearance Solid
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Molecular Weight 140.09
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Formula C5H415N4O
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Color White to off-white
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SMILES
O=C1C2=C([15N]=C[15NH]2)[15NH]C=[15N]1
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Synonyms
Purin-6-ol-15N4; Sarcine-15N4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Talanta
A simple, rapid and sensitive HILIC LC-MS/MS method for simultaneous determination of 16 purine metabolites in plasma and urine. [Abstract]2024 Jan 15:267:125171. PMID: 37696233 -
J Pharm Biomed Anal
A novel UHPLC-MS/MS approach for simultaneous quantification of pyrimidine metabolites in human biofluids. [Abstract]2025 Jun 17:265:117026. PMID: 40544701
Solvent & Solubility
DMSO : 10 mg/mL (71.38 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Saugstad OD, et al. Hypoxanthine as an indicator of hypoxia: its role in health and disease through free radical production. Pediatr Res. 1988 Feb;23(2):143-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.1383 mL | 35.6913 mL | 71.3827 mL | 178.4567 mL |
| 5 mM | 1.4277 mL | 7.1383 mL | 14.2765 mL | 35.6913 mL | |
| 10 mM | 0.7138 mL | 3.5691 mL | 7.1383 mL | 17.8457 mL | |
| 15 mM | 0.4759 mL | 2.3794 mL | 4.7588 mL | 11.8971 mL | |
| 20 mM | 0.3569 mL | 1.7846 mL | 3.5691 mL | 8.9228 mL | |
| 25 mM | 0.2855 mL | 1.4277 mL | 2.8553 mL | 7.1383 mL | |
| 30 mM | 0.2379 mL | 1.1897 mL | 2.3794 mL | 5.9486 mL | |
| 40 mM | 0.1785 mL | 0.8923 mL | 1.7846 mL | 4.4614 mL | |
| 50 mM | 0.1428 mL | 0.7138 mL | 1.4277 mL | 3.5691 mL | |
| 60 mM | 0.1190 mL | 0.5949 mL | 1.1897 mL | 2.9743 mL |
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