1. Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
  2. EGFR
  3. Osimertinib D6

Osimertinib D6 (Synonyms: AZD-9291 D6; Mereletinib D6)

Cat. No.: HY-15772S Purity: 99.70%
Handling Instructions

Osimertinib D6 (AZD-9291 D6) is a deuterium labeled Osimertinib. Osimertinib is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively.

For research use only. We do not sell to patients.

Osimertinib D6 Chemical Structure

Osimertinib D6 Chemical Structure

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1 mg USD 420 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Osimertinib D6 (AZD-9291 D6) is a deuterium labeled Osimertinib. Osimertinib is an irreversible and mutant selective EGFR inhibitor with IC50s of 12 and 1 nM against EGFRL858R and EGFRL858R/T790M, respectively[1].

Molecular Weight

505.64

Formula

C₂₈H₂₇D₆N₇O₂

SMILES

C=CC(NC1=CC(NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2)=C(OC)C=C1N(CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

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Keywords:

Osimertinib D6AZD-9291 D6Mereletinib D6Osimertinib D 6Osimertinib D-6Mereletinib D 6Mereletinib D-6EGFREpidermal growth factor receptorErbB-1HER1Inhibitorinhibitorinhibit

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Osimertinib D6
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HY-15772S
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