L-Valine-13C5,15N,d2
L-Valine-13C5,15N,d2 ((S)-Valine-13C5,15N,d2) is the deuterium, 13C-, and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
For research use only. We do not sell to patients.
- CAS No.: 201417-09-6
- Formula: 13C5H9D215NO2
- Molecular Weight:125.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 201417-09-6
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Unlabeled Cas 72-18-4
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Molecular Weight 125.12
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Formula 13C5H9D215NO2
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SMILES
[13CH3][13C]([13CH3])([2H])[13C@@]([15NH2])([2H])[13C](O)=O
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Synonyms
(S)-Valine-13C5,15N,d2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074(T). Appl Microbiol Biotechnol. 2016 May;100(10):4627-36. [Content Brief]
[2]. Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207. [Content Brief]
[3]. K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69(4):1283-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-Valine-13C5,15N,d2 Related Classifications
HY-N0717S3 Related Classifications
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