N-Acetyl-D-glucosamine-13C8,15N
Based on 1 Customer Validation
N-Acetyl-D-glucosamine-13C8,15N is 13C and 15N labeled N-Acetyl-D-glucosamine (HY-A0132). N-Acetyl-D-glucosamine is a monosaccharide derivative of glucose.
For research use only. We do not sell to patients.
- Purity: 95.0%
- Formula: 13C8H1515NO6
- Molecular Weight:230.13
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 7512-17-6
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Appearance Solid
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Molecular Weight 230.13
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Formula 13C8H1515NO6
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Color White to off-white
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SMILES
O[13C][13C@@](O)[13C@@](O)[13C@](O)[13C@]([13C]=O)[15NH][13C]([13CH3])=O
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Synonyms
N-Acetyl-2-amino-2-deoxy-D-glucose-13C8,15N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : ≥ 10 mg/mL (43.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
DMF : ≥ 0.25 mg/mL (1.09 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Slawson C, et al. O-GlcNAc cycling: how a single sugar post-translational modification is changing the way we think about signaling networks. J Cell Biochem. 2006 Jan 1;97(1):71-83. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMF / DMSO | 1 mM | 4.3454 mL | 21.7268 mL | 43.4537 mL | 108.6342 mL |
| DMSO | 5 mM | 0.8691 mL | 4.3454 mL | 8.6907 mL | 21.7268 mL |
| 10 mM | 0.4345 mL | 2.1727 mL | 4.3454 mL | 10.8634 mL | |
| 15 mM | 0.2897 mL | 1.4485 mL | 2.8969 mL | 7.2423 mL | |
| 20 mM | 0.2173 mL | 1.0863 mL | 2.1727 mL | 5.4317 mL | |
| 25 mM | 0.1738 mL | 0.8691 mL | 1.7381 mL | 4.3454 mL | |
| 30 mM | 0.1448 mL | 0.7242 mL | 1.4485 mL | 3.6211 mL | |
| 40 mM | 0.1086 mL | 0.5432 mL | 1.0863 mL | 2.7159 mL |