Uridine 5'-monophosphate-15N2
Based on 1 Customer Validation
Uridine 5'-monophosphate-15N2 (5'-Uridylic acid-15N2) is the 15N labeled Uridine 5'-monophosphate (HY-101981). Uridine 5'-monophosphate (5'-Uridylic acid) is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
For research use only. We do not sell to patients.
- Purity: 98.0%
- Formula: C9H1315N2O9P
- Molecular Weight:326.17
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 58-97-9
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Appearance Solid
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Molecular Weight 326.17
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Formula C9H1315N2O9P
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Color White to off-white
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SMILES
O[C@H]1[C@@]([H])(O[C@H](COP(O)(O)=O)[C@H]1O)[15N]2C([15NH]C(C=C2)=O)=O
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Synonyms
5'-Uridylic acid-15N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
H2O : 150 mg/mL (459.88 mM; Need ultrasonic)
DMSO : 150 mg/mL (459.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Li G, et al. Uridine/UMP metabolism and their function on the gut in segregated early weaned piglets. Food Funct. 2019 Jul 17;10(7):4081-4089. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 3.0659 mL | 15.3294 mL | 30.6589 mL | 76.6471 mL |
| 5 mM | 0.6132 mL | 3.0659 mL | 6.1318 mL | 15.3294 mL | |
| 10 mM | 0.3066 mL | 1.5329 mL | 3.0659 mL | 7.6647 mL | |
| 15 mM | 0.2044 mL | 1.0220 mL | 2.0439 mL | 5.1098 mL | |
| 20 mM | 0.1533 mL | 0.7665 mL | 1.5329 mL | 3.8324 mL | |
| 25 mM | 0.1226 mL | 0.6132 mL | 1.2264 mL | 3.0659 mL | |
| 30 mM | 0.1022 mL | 0.5110 mL | 1.0220 mL | 2.5549 mL | |
| 40 mM | 0.0766 mL | 0.3832 mL | 0.7665 mL | 1.9162 mL | |
| 50 mM | 0.0613 mL | 0.3066 mL | 0.6132 mL | 1.5329 mL | |
| 60 mM | 0.0511 mL | 0.2555 mL | 0.5110 mL | 1.2775 mL | |
| 80 mM | 0.0383 mL | 0.1916 mL | 0.3832 mL | 0.9581 mL | |
| 100 mM | 0.0307 mL | 0.1533 mL | 0.3066 mL | 0.7665 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Uridine 5'-monophosphate-15N2 Related Classifications
HY-101981S Related Classifications
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