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Midostaurin-d5 (Synonyms: PKC412-d5; CGP 41251-d5)

Cat. No.: HY-10230S
Handling Instructions

Midostaurin-d5 (PKC412-d5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM.

For research use only. We do not sell to patients.

Midostaurin-d5 Chemical Structure

Midostaurin-d5 Chemical Structure

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Description

Midostaurin-d5 (PKC412-d5) is a deuterium labeled Midostaurin. Midostaurin is a multi-targeted protein kinase inhibitor which inhibits PKCα/β/γ, Syk, Flk-1, Akt, PKA, c-Kit, c-Fgr, c-Src, FLT3, PDFRβ and VEGFR1/2 with IC50s ranging from 22-500 nM[1].

Molecular Weight

575.67

Formula

C₃₅H₂₅D₅N₄O₄

SMILES

O=C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N(C)[[email protected]]2[[email protected]@H](OC)[[email protected]@]3(C)N(C4=C5C=CC=C4)C6=C5C7=C(C(NC7)=O)C8=C6N(C9=CC=CC=C98)[[email protected]@](O3)([H])C2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Midostaurin-d5PKC412-d5CGP 41251-d5OthersInhibitorinhibitorinhibit

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