1. Cell Cycle/DNA Damage Metabolic Enzyme/Protease Anti-infection
  2. DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus
  3. Thymidine-15N2

Thymidine-15N2  (Synonyms: DThyd-15N2; NSC-15N2)

Cat. No.: HY-N1150S9 Purity: ≥99.0%
COA Handling Instructions

Thymidine-15N2 is the 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

For research use only. We do not sell to patients.

Thymidine-<sup>15</sup>N<sub>2</sub> Chemical Structure

Thymidine-15N2 Chemical Structure

Size Price Stock Quantity
1 mg USD 350 In-stock
5 mg USD 890 In-stock
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50 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Thymidine-15N2:

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  • Biological Activity

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Description

Thymidine-15N2 is the 15N labeled Thymidine[1]. Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication[2][3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

244.22

Formula

C10H1415N2O5

Unlabeled CAS

50-89-5

Appearance

Solid

Color

White to off-white

SMILES

O=C1[15N](C=C(C([15NH]1)=O)C)[C@]2([H])O[C@@H]([C@H](C2)O)CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (204.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (204.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0947 mL 20.4733 mL 40.9467 mL
5 mM 0.8189 mL 4.0947 mL 8.1893 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 4.0947 mL 20.4733 mL 40.9467 mL 102.3667 mL
5 mM 0.8189 mL 4.0947 mL 8.1893 mL 20.4733 mL
10 mM 0.4095 mL 2.0473 mL 4.0947 mL 10.2367 mL
15 mM 0.2730 mL 1.3649 mL 2.7298 mL 6.8244 mL
20 mM 0.2047 mL 1.0237 mL 2.0473 mL 5.1183 mL
25 mM 0.1638 mL 0.8189 mL 1.6379 mL 4.0947 mL
30 mM 0.1365 mL 0.6824 mL 1.3649 mL 3.4122 mL
40 mM 0.1024 mL 0.5118 mL 1.0237 mL 2.5592 mL
50 mM 0.0819 mL 0.4095 mL 0.8189 mL 2.0473 mL
60 mM 0.0682 mL 0.3412 mL 0.6824 mL 1.7061 mL
80 mM 0.0512 mL 0.2559 mL 0.5118 mL 1.2796 mL
100 mM 0.0409 mL 0.2047 mL 0.4095 mL 1.0237 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thymidine-15N2
Cat. No.:
HY-N1150S9
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