Benzyl benzoate-d12
Based on 1 publication(s) in Google Scholar
Benzyl benzoate-d12 is the deuterium labeled Benzyl benzoate. Benzyl benzoate (Benzoic acid benzyl ester) is a fragrance ingredient in cosmetic products. Benzyl benzoate can be used for the research of Scabies and Demodex-associated inflammatory skin conditions.
For research use only. We do not sell to patients.
- Purity: 99.46%
- CAS No.: 352431-26-6
- Formula: C14D12O2
- Molecular Weight:224.32
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Benzyl benzoate-d12
MoreAll Parasite Isoforms
MoreAll Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 352431-26-6
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Unlabeled Cas 120-51-4
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Appearance Liquid
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Molecular Weight 224.32
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Formula C14D12O2
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Color Colorless to light yellow
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SMILES
[2H]C1=C([2H])C([2H])=C([2H])C([2H])=C1C([2H])([2H])OC(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O
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Synonyms
Benzoic acid benzyl ester-d12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Nature
2025 Sep;645(8079):208-217. PMID: 40702180
Solvent & Solubility
DMSO : 100 mg/mL (445.79 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Johnson W, et, al. Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate. Int J Toxicol. Nov/Dec 2017;36(3_suppl):5S-30S. [Content Brief]
[3]. Jacob S, et, al. Treatment of Demodex-associated inflammatory skin conditions: A systematic review. Dermatol Ther. 2019 Nov32(6):e13103. [Content Brief]
[4]. Dressler C, et, al. The Treatment of Scabies. Dtsch Arztebl Int. 2016 Nov 14113(45):757-762. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.4579 mL | 22.2896 mL | 44.5792 mL | 111.4479 mL |
| 5 mM | 0.8916 mL | 4.4579 mL | 8.9158 mL | 22.2896 mL | |
| 10 mM | 0.4458 mL | 2.2290 mL | 4.4579 mL | 11.1448 mL | |
| 15 mM | 0.2972 mL | 1.4860 mL | 2.9719 mL | 7.4299 mL | |
| 20 mM | 0.2229 mL | 1.1145 mL | 2.2290 mL | 5.5724 mL | |
| 25 mM | 0.1783 mL | 0.8916 mL | 1.7832 mL | 4.4579 mL | |
| 30 mM | 0.1486 mL | 0.7430 mL | 1.4860 mL | 3.7149 mL | |
| 40 mM | 0.1114 mL | 0.5572 mL | 1.1145 mL | 2.7862 mL | |
| 50 mM | 0.0892 mL | 0.4458 mL | 0.8916 mL | 2.2290 mL | |
| 60 mM | 0.0743 mL | 0.3715 mL | 0.7430 mL | 1.8575 mL | |
| 80 mM | 0.0557 mL | 0.2786 mL | 0.5572 mL | 1.3931 mL | |
| 100 mM | 0.0446 mL | 0.2229 mL | 0.4458 mL | 1.1145 mL |
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