Palmitoyl serinol-d5
Palmitoyl serinol-d5 is the deuterium labeled Palmitoyl serinol. Palmitoyl serinol (N-Palmitoyl serinol) is an analog of the endocannabinoid N-palmitoyl ethanolamine (PEA). Palmitoyl serinol improves the epidermal permeability barrier in both normal and inflamed skin.
For research use only. We do not sell to patients.
- CAS No.: 946524-35-2
- Formula: C19H34D5NO3
- Molecular Weight:334.55
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 946524-35-2
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Unlabeled Cas 126127-31-9
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Molecular Weight 334.55
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Formula C19H34D5NO3
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SMILES
CCCCCCCCCCCCCCCC(NC(C([2H])([2H])O)([2H])C([2H])([2H])O)=O
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Synonyms
N-Palmitoyl serinol-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Shin KO, et al. N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. Int J Mol Sci. 2021;22(15):8302. Published 2021 Aug 2. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)