1. Membrane Transporter/Ion Channel
    Apoptosis
  2. Proton Pump
    Apoptosis
  3. Rabeprazole-d3 sodium

Rabeprazole-d3 sodium (Synonyms: LY307640-d3 sodium)

Cat. No.: HY-B0656AS1
Handling Instructions

Rabeprazole-d3 (LY307640-d3) sodiumis the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.

For research use only. We do not sell to patients.

Rabeprazole-d3 sodium Chemical Structure

Rabeprazole-d3 sodium Chemical Structure

CAS No. : 1216494-11-9

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Description

Rabeprazole-d3 (LY307640-d3) sodiumis the deuterium labeled Rabeprazole sodium. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

384.44

Formula

C18H17D3N3NaO3S

CAS No.
SMILES

O=S(C1=NC2=CC=CC=C2N1[Na])CC3=NC=CC(OCCCOC([2H])([2H])[2H])=C3C

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Rabeprazole-d3 sodium
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