1. Immunology/Inflammation
  2. COX
  3. Phenacetin-d5

Phenacetin-d5  (Synonyms: Acetophenetidin-d5)

Cat. No.: HY-B0476S Purity: 98.51%
COA Handling Instructions

Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats.

For research use only. We do not sell to patients.

Phenacetin-d5 Chemical Structure

Phenacetin-d5 Chemical Structure

CAS No. : 69323-74-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 347 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 347 In-stock
Estimated Time of Arrival: December 31
Solid
1 mg USD 108 In-stock
Estimated Time of Arrival: December 31
5 mg USD 315 In-stock
Estimated Time of Arrival: December 31
10 mg USD 500 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1000 In-stock
Estimated Time of Arrival: December 31
50 mg USD 1600 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Description

Phenacetin-d5 (Acetophenetidin-d5) is the deuterium labeled Phenacetin. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

184.25

Formula

C10H8D5NO2

CAS No.
SMILES

CC(NC1=CC=C(C=C1)OC([2H])([2H])C([2H])([2H])[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (542.74 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.4274 mL 27.1370 mL 54.2741 mL
5 mM 1.0855 mL 5.4274 mL 10.8548 mL
10 mM 0.5427 mL 2.7137 mL 5.4274 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phenacetin-d5
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HY-B0476S
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