Levoglucosan-d7
Based on 1 Customer Validation
Levoglucosan-d7 is the deuterium labeled Levoglucosan. Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 2483832-05-7
- Formula: C6H3D7O5
- Molecular Weight:169.18
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2483832-05-7
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Appearance Solid
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Molecular Weight 169.18
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Formula C6H3D7O5
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Color White to off-white
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SMILES
O[C@]1([2H])[C@]2([2H])O[C@@]([C@]([C@@]1([2H])O)([2H])O)([2H])OC2([2H])[2H]
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Synonyms
1,6-Anhydro-β-D-glucopyranose-d7; 1,6-Anhydro-β-D-glucose-d7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (591.09 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Kuritani Y, et al. Conversion of levoglucosan into glucose by the coordination of four enzymes through oxidation, elimination, hydration, and reduction. Sci Rep. 2020;10(1):20066. Published 2020 Nov 18. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.9109 mL | 29.5543 mL | 59.1086 mL | 147.7716 mL |
| 5 mM | 1.1822 mL | 5.9109 mL | 11.8217 mL | 29.5543 mL | |
| 10 mM | 0.5911 mL | 2.9554 mL | 5.9109 mL | 14.7772 mL | |
| 15 mM | 0.3941 mL | 1.9703 mL | 3.9406 mL | 9.8514 mL | |
| 20 mM | 0.2955 mL | 1.4777 mL | 2.9554 mL | 7.3886 mL | |
| 25 mM | 0.2364 mL | 1.1822 mL | 2.3643 mL | 5.9109 mL | |
| 30 mM | 0.1970 mL | 0.9851 mL | 1.9703 mL | 4.9257 mL | |
| 40 mM | 0.1478 mL | 0.7389 mL | 1.4777 mL | 3.6943 mL | |
| 50 mM | 0.1182 mL | 0.5911 mL | 1.1822 mL | 2.9554 mL | |
| 60 mM | 0.0985 mL | 0.4926 mL | 0.9851 mL | 2.4629 mL | |
| 80 mM | 0.0739 mL | 0.3694 mL | 0.7389 mL | 1.8471 mL | |
| 100 mM | 0.0591 mL | 0.2955 mL | 0.5911 mL | 1.4777 mL |