Maribavir-d6
Based on 1 Customer Validation
Maribavir-d6 (1263W94-d6) is a deuterium labeled Maribavir (HY-16305). Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM.
For research use only. We do not sell to patients.
- Purity: 99.98%
- Formula: C15H13D6Cl2N3O4
- Molecular Weight:382.27
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 176161-24-3
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Appearance Solid
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Molecular Weight 382.27
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Formula C15H13D6Cl2N3O4
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Color White to off-white
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SMILES
ClC1=C(Cl)C=C2C(N=C(NC(C([2H])([2H])[2H])C([2H])([2H])[2H])N2[C@@H]3[C@@H](O)[C@@H](O)[C@H](CO)O3)=C1
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Synonyms
1263W94-d6; BW1263W94-d6; GW257406X-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (261.60 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6160 mL | 13.0798 mL | 26.1595 mL | 65.3988 mL |
| 5 mM | 0.5232 mL | 2.6160 mL | 5.2319 mL | 13.0798 mL | |
| 10 mM | 0.2616 mL | 1.3080 mL | 2.6160 mL | 6.5399 mL | |
| 15 mM | 0.1744 mL | 0.8720 mL | 1.7440 mL | 4.3599 mL | |
| 20 mM | 0.1308 mL | 0.6540 mL | 1.3080 mL | 3.2699 mL | |
| 25 mM | 0.1046 mL | 0.5232 mL | 1.0464 mL | 2.6160 mL | |
| 30 mM | 0.0872 mL | 0.4360 mL | 0.8720 mL | 2.1800 mL | |
| 40 mM | 0.0654 mL | 0.3270 mL | 0.6540 mL | 1.6350 mL | |
| 50 mM | 0.0523 mL | 0.2616 mL | 0.5232 mL | 1.3080 mL | |
| 60 mM | 0.0436 mL | 0.2180 mL | 0.4360 mL | 1.0900 mL | |
| 80 mM | 0.0327 mL | 0.1635 mL | 0.3270 mL | 0.8175 mL | |
| 100 mM | 0.0262 mL | 0.1308 mL | 0.2616 mL | 0.6540 mL |