10-Formylfolic acid-d4
Based on 1 Customer Validation
10-Formylfolic acid-d4 is the deuterated-labeled 10-Formylfolic acid (HY-124350). 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase, with an IC50 of 80 nM against the rat enzyme. 10-Formylfolic acid also acts as an orally active folate source and a growth factor for specific bacteria. 10-Formylfolic acid supports growth and increases plasma folate levels; its absorption and metabolism patterns are similar to those of folic acid, but its liver retention is slightly higher. It exhibits high folate activity in microbial assays, serves as a growth factor for Enterococcus faecalis and Lactobacillus casei, aids folate nutrient supply, and may exert cell regulatory functions.
For research use only. We do not sell to patients.
- CAS No.: 461426-41-5
- Formula: C20H15D4N7O7
- Molecular Weight:473.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 461426-41-5
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Unlabeled CAS 134-05-4
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Molecular Weight 473.43
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Formula C20H15D4N7O7
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SMILES
O=C1C2=NC(CN(C3=C([2H])C([2H])=C(C([2H])=C3[2H])C(N[C@H](C(O)=O)CCC(O)=O)=O)C=O)=CNC2=NC(N)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)