134-05-4
134-05-4
Chemical Structure
10-Formylfolic acid
- CAS No.: 134-05-4
- Formula:C20H19N7O7
- Molecular Weight:469.41
IUPAC Name: (4-(N-((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)formamido)benzoyl)-L-glutamic acid
InChIKey: UGWUWNVTCLDEOG-ZDUSSCGKSA-N
SMILES: O=C(O)[C@@H](NC(C1=CC=C(N(C=O)CC2=NC3=C(N=C2)N=C(N)NC3=O)C=C1)=O)CCC(O)=O
Biological Activity: 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. 10-Formylfolic acid be used as an early indicator of leukemia[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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10-Formylfolic acid | 94.49% | 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. 10-Formylfolic acid be used as an early indicator of leukemia. | ||||||||||||||||||||
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10-Formylfolic acid (Standard) | ≥98% | 10-Formylfolic acid (Standard) is the analytical standard of 10-Formylfolic acid. This product is intended for research and analytical applications. 10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase. 10-Formylfolic acid be used as an early indicator of leukemia. | ||||||||||||||||||||
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10-Formylfolic acid-d4 | 10-Formylfolic acid-d4 is the deuterium labeled 10-Formylfolic acid. | |||||||||||||||||||||
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References
- [1]. M D'Urso-Scott, et al. Formation of 10-Formylfolic Acid, a Potent Inhibitor of Dihydrofolate Reductase, in Rat Liver Slices Incubated with Folic Acid. Proc Natl Acad Sci U S A. 1974 Jul;71(7):2736-9. [Content Brief]
- [2]. J E Baggott, et al. 10-Formyl-dihydrofolic acid is bioactive in human leukemia cells. J Nutr. 1999 Jul;129(7):1315-8. [Content Brief]
