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Cat. No.: HY-12753S1

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Debutyldronedarone-d₆ hydrochloride

(Synonyms: SR35021-dd₆ hydrochloride)

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Debutyldronedarone-d₆ hydrochloride (SR35021-d₆ hydrochloride) is the deuterated-labeled Debutyldronedarone (HY-12753). Debutyldronedarone (SR35021) is a Cytochrome P450 enzyme inhibitor and a Thyroid Hormone Receptor inhibitor, and it is a metabolite of Dronedarone (HY-A0016). Debutyldronedarone inhibits the binding of T3 to TRα1 and TRβ1. Debutyldronedarone reduces the incidence of reperfusion-induced ventricular fibrillation in anesthetized rats, while decreasing their heart rate and blood pressure. Debutyldronedarone can be used in studies related to ventricular fibrillation and atrial fibrillation.

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Pureté: 99.27%
CAS No.: 1346598-70-6
Formule: C₂₇H₃₁D₆ClN₂O₅S
Masse moléculaire:543.15

Stockage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Debutyldronedarone-d₆ hydrochloride Chemical Structure

CAS No.: 1346598-70-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Application
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Cytochrome P450 :

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 1346598-70-6
Unlabeled Cas 141626-35-9
Appearance Solid
Masse moléculaire 543.15
Formule C₂₇H₃₁D₆ClN₂O₅S
Color White to off-white
SMILES

CS(=O)(NC1=CC=C(C2=C1)OC(CCCC)=C2C(C3=CC=C(C=C3)OC([2H])(C([2H])(C([2H])(NCCCC)[2H])[2H])[2H])=O)=O.Cl[H]
Synonyms

SR35021-dd₆ hydrochloride
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Therapeutic Goods Administration. Australian Public Assessment Report for Dronedarone Hydrochloride, submission PM-2008-3045-3, Australian Government Department of Health and Ageing, 2008.

[2]. Van Beeren HC, et al. Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence. Endocrinology. 2003 Feb;144(2):552-8. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Debutyldronedarone-d₆ hydrochloride

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Debutyldronedarone-d6 hydrochloride

Voir tous les produits spécifiques à Isoform Cytochrome P450

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Debutyldronedarone-d6 hydrochloride Related Classifications

HY-12753S1 Related Classifications

Debutyldronedarone-d₆ hydrochloride

Debutyldronedarone-d₆ hydrochloride Related Classifications