Enzalutamide-d6
Based on 1 Customer Validation
Enzalutamide-d6 (MDV3100-d6) is a deuterium labeled Enzalutamide (MDV3100). Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 1443331-94-9
- Formula: C21H10D6F4N4O2S
- Molecular Weight:470.47
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1443331-94-9
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Unlabeled Cas 915087-33-1
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Appearance Solid
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Molecular Weight 470.47
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Formula C21H10D6F4N4O2S
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Color White to off-white
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SMILES
O=C(NC)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C2=O)C=C1F
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Synonyms
MDV3100-d6
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMF : ≥ 25 mg/mL (53.14 mM)
DMSO : ≥ 20 mg/mL (42.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : ≥ 0.5 mg/mL (1.06 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO / DMF | 1 mM | 2.1255 mL | 10.6277 mL | 21.2553 mL | 53.1384 mL |
| DMSO / DMF | 5 mM | 0.4251 mL | 2.1255 mL | 4.2511 mL | 10.6277 mL |
| 10 mM | 0.2126 mL | 1.0628 mL | 2.1255 mL | 5.3138 mL | |
| 15 mM | 0.1417 mL | 0.7085 mL | 1.4170 mL | 3.5426 mL | |
| 20 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6569 mL | |
| 25 mM | 0.0850 mL | 0.4251 mL | 0.8502 mL | 2.1255 mL | |
| 30 mM | 0.0709 mL | 0.3543 mL | 0.7085 mL | 1.7713 mL | |
| 40 mM | 0.0531 mL | 0.2657 mL | 0.5314 mL | 1.3285 mL | |
| DMF | 50 mM | 0.0425 mL | 0.2126 mL | 0.4251 mL | 1.0628 mL |
Enzalutamide-d6 Related Classifications
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