L-Valine-13C5,15N
Based on 1 Customer Validation
L-Valine-13C5,15N ((S)-Valine-13C5,15) is the 13C- and 15N-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
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- Pureza: 99.64%
- No. CAS: 202407-30-5
- Fòrmula: 13C5H1115NO2
- Peso molecular:123.10
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 202407-30-5
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Unlabeled Cas 72-18-4
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Appearance Solid
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Peso molecular 123.10
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Fòrmula 13C5H1115NO2
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Color White to off-white
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SMILES
[13CH3][13CH]([13CH3])[13C@H]([15NH2])[13C](O)=O
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Synonyms
(S)-Valine-13C5,15N
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
H2O : 35.71 mg/mL (290.09 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074(T). Appl Microbiol Biotechnol. 2016 May;100(10):4627-36. [Content Brief]
[2]. Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207. [Content Brief]
[3]. K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69(4):1283-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.1235 mL | 40.6174 mL | 81.2348 mL | 203.0869 mL |
| 5 mM | 1.6247 mL | 8.1235 mL | 16.2470 mL | 40.6174 mL | |
| 10 mM | 0.8123 mL | 4.0617 mL | 8.1235 mL | 20.3087 mL | |
| 15 mM | 0.5416 mL | 2.7078 mL | 5.4157 mL | 13.5391 mL | |
| 20 mM | 0.4062 mL | 2.0309 mL | 4.0617 mL | 10.1543 mL | |
| 25 mM | 0.3249 mL | 1.6247 mL | 3.2494 mL | 8.1235 mL | |
| 30 mM | 0.2708 mL | 1.3539 mL | 2.7078 mL | 6.7696 mL | |
| 40 mM | 0.2031 mL | 1.0154 mL | 2.0309 mL | 5.0772 mL | |
| 50 mM | 0.1625 mL | 0.8123 mL | 1.6247 mL | 4.0617 mL | |
| 60 mM | 0.1354 mL | 0.6770 mL | 1.3539 mL | 3.3848 mL | |
| 80 mM | 0.1015 mL | 0.5077 mL | 1.0154 mL | 2.5386 mL | |
| 100 mM | 0.0812 mL | 0.4062 mL | 0.8123 mL | 2.0309 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Valine-13C5,15N Related Classifications
HY-N0717S1 Related Classifications
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