L-Valine-13C5
Based on 1 publication(s) in Google Scholar
L-Valine-13C5 ((S)-Valine-13C5) is the 13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
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- Reinheit: 99.75%
- CAS. Nr.: 55443-52-2
- Formel: 13C5H11NO2
- Molecular Weight:122.11
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) L-Valine-13C5
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 55443-52-2
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Unlabeled CAS 72-18-4
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Appearance Solid
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Molecular Weight 122.11
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Formel 13C5H11NO2
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Color White to off-white
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SMILES
[13CH3][13CH]([13CH3])[13C@H](N)[13C](O)=O
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Synonyms
(S)-Valine-13C5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 50 mg/mL (409.47 mM; ultrasonic and warming and heat to 80°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074(T). Appl Microbiol Biotechnol. 2016 May;100(10):4627-36. [Content Brief]
[2]. Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207. [Content Brief]
[3]. K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69(4):1283-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.1893 mL | 40.9467 mL | 81.8934 mL | 204.7334 mL |
| 5 mM | 1.6379 mL | 8.1893 mL | 16.3787 mL | 40.9467 mL | |
| 10 mM | 0.8189 mL | 4.0947 mL | 8.1893 mL | 20.4733 mL | |
| 15 mM | 0.5460 mL | 2.7298 mL | 5.4596 mL | 13.6489 mL | |
| 20 mM | 0.4095 mL | 2.0473 mL | 4.0947 mL | 10.2367 mL | |
| 25 mM | 0.3276 mL | 1.6379 mL | 3.2757 mL | 8.1893 mL | |
| 30 mM | 0.2730 mL | 1.3649 mL | 2.7298 mL | 6.8244 mL | |
| 40 mM | 0.2047 mL | 1.0237 mL | 2.0473 mL | 5.1183 mL | |
| 50 mM | 0.1638 mL | 0.8189 mL | 1.6379 mL | 4.0947 mL | |
| 60 mM | 0.1365 mL | 0.6824 mL | 1.3649 mL | 3.4122 mL | |
| 80 mM | 0.1024 mL | 0.5118 mL | 1.0237 mL | 2.5592 mL | |
| 100 mM | 0.0819 mL | 0.4095 mL | 0.8189 mL | 2.0473 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Valine-13C5 Related Classifications
HY-N0717S6 Related Classifications
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