1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. (±)-1,2-Propanediol-d6

(±)-1,2-Propanediol-d6  (Synonyms: 1,2-(RS)-Propanediol-d6; 1,2-Propylene glycol-d6; Propylene glycol-d6)

Cat. No.: HY-Y0921S2 Purity: ≥99.0%
COA Handling Instructions

(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol[1]. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[2].

For research use only. We do not sell to patients.

(±)-1,2-Propanediol-d<sub>6</sub> Chemical Structure

(±)-1,2-Propanediol-d6 Chemical Structure

CAS No. : 52910-80-2

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1 mg USD 30 In-stock
5 mg USD 50 In-stock
10 mg USD 70 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of (±)-1,2-Propanediol-d6:

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Description

(±)-1,2-Propanediol-d6 is the deuterium labeled (±)-1,2-Propanediol[1]. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

82.13

Formula

C3H2D6O2

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

OC([2H])([2H])C(O)([2H])C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (3043.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 12.1758 mL 60.8791 mL 121.7582 mL
5 mM 2.4352 mL 12.1758 mL 24.3516 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

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=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 12.1758 mL 60.8791 mL 121.7582 mL 304.3955 mL
5 mM 2.4352 mL 12.1758 mL 24.3516 mL 60.8791 mL
10 mM 1.2176 mL 6.0879 mL 12.1758 mL 30.4395 mL
15 mM 0.8117 mL 4.0586 mL 8.1172 mL 20.2930 mL
20 mM 0.6088 mL 3.0440 mL 6.0879 mL 15.2198 mL
25 mM 0.4870 mL 2.4352 mL 4.8703 mL 12.1758 mL
30 mM 0.4059 mL 2.0293 mL 4.0586 mL 10.1465 mL
40 mM 0.3044 mL 1.5220 mL 3.0440 mL 7.6099 mL
50 mM 0.2435 mL 1.2176 mL 2.4352 mL 6.0879 mL
60 mM 0.2029 mL 1.0147 mL 2.0293 mL 5.0733 mL
80 mM 0.1522 mL 0.7610 mL 1.5220 mL 3.8049 mL
100 mM 0.1218 mL 0.6088 mL 1.2176 mL 3.0440 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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(±)-1,2-Propanediol-d6 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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(±)-1,2-Propanediol-d6
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