(±)-Leucine-d10
Based on 1 Customer Validation
(±)-Leucine-d10 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 29909-01-1
- Formula: C6H3D10NO2
- Molecular Weight:141.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 29909-01-1
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Unlabeled Cas 328-39-2
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Appearance Solid
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Molecular Weight 141.23
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Formula C6H3D10NO2
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Color White to off-white
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C([2H])([2H])C(N)([2H])C(O)=O
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Synonyms
DL-Leucine-d10; (RS)-Leucine-d10
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 12.5 mg/mL (88.51 mM; ultrasonic and warming and heat to 80°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 10 mg/mL (70.81 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.0806 mL | 35.4032 mL | 70.8065 mL | 177.0162 mL |
| 5 mM | 1.4161 mL | 7.0806 mL | 14.1613 mL | 35.4032 mL | |
| 10 mM | 0.7081 mL | 3.5403 mL | 7.0806 mL | 17.7016 mL | |
| 15 mM | 0.4720 mL | 2.3602 mL | 4.7204 mL | 11.8011 mL | |
| 20 mM | 0.3540 mL | 1.7702 mL | 3.5403 mL | 8.8508 mL | |
| 25 mM | 0.2832 mL | 1.4161 mL | 2.8323 mL | 7.0806 mL | |
| 30 mM | 0.2360 mL | 1.1801 mL | 2.3602 mL | 5.9005 mL | |
| 40 mM | 0.1770 mL | 0.8851 mL | 1.7702 mL | 4.4254 mL | |
| 50 mM | 0.1416 mL | 0.7081 mL | 1.4161 mL | 3.5403 mL | |
| 60 mM | 0.1180 mL | 0.5901 mL | 1.1801 mL | 2.9503 mL | |
| 80 mM | 0.0885 mL | 0.4425 mL | 0.8851 mL | 2.2127 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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