L-Histidine-d3 hydrochloride hydrate
L-Histidine-d3 hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
For research use only. We do not sell to patients.
- Formula: C6H9D3ClN3O3
- Molecular Weight:212.65
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Molecular Weight 212.65
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Formula C6H9D3ClN3O3
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SMILES
OC([C@](N)([2H])CC1=C([2H])N=C([2H])N1)=O.Cl.O
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Synonyms
H-His-OH-d3 hydrochloride hydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Palomba L, et al., Low levels of hydrogen peroxide and L-histidine induce DNA double-strand breakage and apoptosis. Eur J Pharmacol. 1996 Dec 27;318(1):167-73. [Content Brief]
[2]. Kawahara M, et al., D-histidine and L-histidine attenuate zinc-induced neuronal death in GT1-7 cells. Metallomics. 2013 May;5(5):453-60. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-Histidine-d3 hydrochloride hydrate Related Classifications
HY-W014423S7 Related Classifications
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