(S)-Malic acid-13C4
Based on 1 Customer Validation
(S)-Malic acid-13C4 is the 13C labeled S-Malic acid (HY-Y1069).
For research use only. We do not sell to patients.
- Purity: 98.2%
- CAS No.: 150992-96-4
- Formula: 13C4H6O5
- Molecular Weight:138.06
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
It is showed that ME is essential for (S)-2-Hydroxysuccinic acid (L-malic acid) utilization in L. casei. Furthermore, deletion of either the gene encoding the histidine kinase or the response regulator of the TC system resulted in the loss of the ability to grow on (S)-2-Hydroxysuccinic acid, thus indicating that the cognate TC system regulates and is essential for the expression of ME. Transcriptional analyses shows that expression of maeE is induced in the presence of (S)-2-Hydroxysuccinic acid and repressed by glucose, whereas TC system expression is induced by (S)-2-Hydroxysuccinic acid and is not repressed by glucose[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 150992-96-4
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Unlabeled Cas 97-67-6
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Appearance Solid
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Molecular Weight 138.06
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Formula 13C4H6O5
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Color White to off-white
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SMILES
O[13C]([13CH2][13C@H](O)[13C](O)=O)=O
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Synonyms
(S)-Hydroxybutanedioic acid-13C4; (S)-E 296-13C4; L-Malic acid-13C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (724.32 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.2432 mL | 36.2161 mL | 72.4323 mL | 181.0807 mL |
| 5 mM | 1.4486 mL | 7.2432 mL | 14.4865 mL | 36.2161 mL | |
| 10 mM | 0.7243 mL | 3.6216 mL | 7.2432 mL | 18.1081 mL | |
| 15 mM | 0.4829 mL | 2.4144 mL | 4.8288 mL | 12.0720 mL | |
| 20 mM | 0.3622 mL | 1.8108 mL | 3.6216 mL | 9.0540 mL | |
| 25 mM | 0.2897 mL | 1.4486 mL | 2.8973 mL | 7.2432 mL | |
| 30 mM | 0.2414 mL | 1.2072 mL | 2.4144 mL | 6.0360 mL | |
| 40 mM | 0.1811 mL | 0.9054 mL | 1.8108 mL | 4.5270 mL | |
| 50 mM | 0.1449 mL | 0.7243 mL | 1.4486 mL | 3.6216 mL | |
| 60 mM | 0.1207 mL | 0.6036 mL | 1.2072 mL | 3.0180 mL | |
| 80 mM | 0.0905 mL | 0.4527 mL | 0.9054 mL | 2.2635 mL | |
| 100 mM | 0.0724 mL | 0.3622 mL | 0.7243 mL | 1.8108 mL |
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