Carazolol-d7
Based on 1 Customer Validation
Carazolol-d7 is the deuterium labeled Carazolol (HY-107327). Carazolol is a highly potent antagonist of β1/β2 adrenoceptor. Carazolol is also a potent, selective β3-adrenoceptor agonist. Carazolol can be used in the research of hypertension.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 1173021-02-7
- Formula: C18H15D7N2O2
- Molecular Weight:305.42
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Adrenergic Receptor Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1173021-02-7
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Unlabeled Cas 57775-29-8
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Appearance Solid
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Molecular Weight 305.42
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Formula C18H15D7N2O2
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Color Off-white to light yellow
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SMILES
[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NCC(O)COC1=C2C3=CC=CC=C3NC2=CC=C1
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Synonyms
(±)-Carazolol-d7; DL-Carazolol-d7; Suacron-d7
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (327.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2742 mL | 16.3709 mL | 32.7418 mL | 81.8545 mL |
| 5 mM | 0.6548 mL | 3.2742 mL | 6.5484 mL | 16.3709 mL | |
| 10 mM | 0.3274 mL | 1.6371 mL | 3.2742 mL | 8.1854 mL | |
| 15 mM | 0.2183 mL | 1.0914 mL | 2.1828 mL | 5.4570 mL | |
| 20 mM | 0.1637 mL | 0.8185 mL | 1.6371 mL | 4.0927 mL | |
| 25 mM | 0.1310 mL | 0.6548 mL | 1.3097 mL | 3.2742 mL | |
| 30 mM | 0.1091 mL | 0.5457 mL | 1.0914 mL | 2.7285 mL | |
| 40 mM | 0.0819 mL | 0.4093 mL | 0.8185 mL | 2.0464 mL | |
| 50 mM | 0.0655 mL | 0.3274 mL | 0.6548 mL | 1.6371 mL | |
| 60 mM | 0.0546 mL | 0.2728 mL | 0.5457 mL | 1.3642 mL | |
| 80 mM | 0.0409 mL | 0.2046 mL | 0.4093 mL | 1.0232 mL | |
| 100 mM | 0.0327 mL | 0.1637 mL | 0.3274 mL | 0.8185 mL |