2. GPCR/G Protein Neuronal Signaling Autophagy Apoptosis
  3. 5-HT Receptor Dopamine Receptor mAChR Adrenergic Receptor Autophagy Mitophagy Apoptosis
  4. Olanzapine-d3

Olanzapine-d3  (Synonyms: LY170053-d3)

Cat. No.: HY-14541S Purity: 99.09%
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Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2].

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Olanzapine-d<sub>3</sub> Chemical Structure

Olanzapine-d3 Chemical Structure

CAS No. : 786686-79-1

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Based on 1 publication(s) in Google Scholar

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Description

Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2].

IC50 & Target

D3 Receptor

 

mAChR1

 

Molecular Weight

315.45

Formula

C17H17D3N4S
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Olanzapine-d3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Olanzapine-d3786686-79-1LY170053-d35-HT ReceptorDopamine ReceptormAChRAdrenergic ReceptorAutophagyMitophagyApoptosisSerotonin Receptor5-hydroxytryptamine ReceptorMuscarinic acetylcholine receptorBeta ReceptorMitochondrial AutophagyInhibitorinhibitorinhibit

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