1. GPCR/G Protein
    Neuronal Signaling
    Autophagy
    Apoptosis
  2. 5-HT Receptor
    Dopamine Receptor
    mAChR
    Adrenergic Receptor
    Autophagy
    Mitophagy
    Apoptosis
  3. Olanzapine D3

Olanzapine D3 (Synonyms: LY170053 D3)

Cat. No.: HY-14541S
Handling Instructions

Olanzapine D3 (LY170053 D3) is the deuterium labeled Olanzapine. Olanzapine is a selective monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic.

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Olanzapine D3 Chemical Structure

Olanzapine D3 Chemical Structure

CAS No. : 786686-79-1

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Description

Olanzapine D3 (LY170053 D3) is the deuterium labeled Olanzapine. Olanzapine is a selective monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM). Olanzapine is an atypical antipsychotic[1][2].

Molecular Weight

315.45

Formula

C₁₇H₁₇D₃N₄S

CAS No.

786686-79-1

SMILES

[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]

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Keywords:

Olanzapine D3LY170053 D3Olanzapine D 3Olanzapine D-35-HT ReceptorDopamine ReceptormAChRAdrenergic ReceptorAutophagyMitophagyApoptosisSerotonin Receptor5-hydroxytryptamine ReceptorMuscarinic acetylcholine receptorBeta ReceptorMitochondrial AutophagyInhibitorinhibitorinhibit

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