L-Alanine-13C2,15N
Based on 1 Customer Validation
L-Alanine-13C2,15N is the 13C- and 15N-labeled L-Alanine. L-Alanine is a non-essential amino acid, involved in sugar and acid metabolism, increases immunity, and provides energy for muscle tissue, brain, and central nervous system.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 312623-85-1
- Formula: C13C2H715NO2
- Molecular Weight:92.07
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 312623-85-1
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Unlabeled Cas 56-41-7
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Appearance Solid
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Molecular Weight 92.07
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Formula C13C2H715NO2
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Color White to off-white
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SMILES
O[13C]([13C@@H]([15NH2])C)=O
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Synonyms
L-2-Aminopropionic acid-13C2,15N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 200 mg/mL (2172.26 mM; Need ultrasonic)
DMSO : 1 mg/mL (10.86 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Nagashima T, et al. Selective Elimination of Human Induced Pluripotent Stem Cells Using Medium with High Concentration of L-Alanine. Sci Rep. 2018 Aug 20;8(1):12427. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 10.8613 mL | 54.3065 mL | 108.6130 mL | 271.5325 mL |
| 5 mM | 2.1723 mL | 10.8613 mL | 21.7226 mL | 54.3065 mL | |
| 10 mM | 1.0861 mL | 5.4307 mL | 10.8613 mL | 27.1533 mL | |
| H2O | 15 mM | 0.7241 mL | 3.6204 mL | 7.2409 mL | 18.1022 mL |
| 20 mM | 0.5431 mL | 2.7153 mL | 5.4307 mL | 13.5766 mL | |
| 25 mM | 0.4345 mL | 2.1723 mL | 4.3445 mL | 10.8613 mL | |
| 30 mM | 0.3620 mL | 1.8102 mL | 3.6204 mL | 9.0511 mL | |
| 40 mM | 0.2715 mL | 1.3577 mL | 2.7153 mL | 6.7883 mL | |
| 50 mM | 0.2172 mL | 1.0861 mL | 2.1723 mL | 5.4307 mL | |
| 60 mM | 0.1810 mL | 0.9051 mL | 1.8102 mL | 4.5255 mL | |
| 80 mM | 0.1358 mL | 0.6788 mL | 1.3577 mL | 3.3942 mL | |
| 100 mM | 0.1086 mL | 0.5431 mL | 1.0861 mL | 2.7153 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Alanine-13C2,15N Related Classifications
HY-N0229S15 Related Classifications
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