2. Others Metabolic Enzyme/Protease Immunology/Inflammation Apoptosis NF-κB
  3. Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Isotope-Labeled Compounds
  4. L-Histidine-d5 hydrochloride hydrate

L-Histidine-d5 hydrochloride hydrate  (Synonyms: H-His-OH-d5 hydrochloride hydrate)

Cat. No.: HY-W014423S4 Purity: 99.96%
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Handling Instructions Technical Support

L-Histidine-d5 hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.

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L-Histidine-d<sub>5</sub> hydrochloride hydrate

L-Histidine-d5 hydrochloride hydrate 화학구조

CAS No. : 2483831-75-8

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
50 mg 견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
100 mg 견적 받기 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
200 mg   견적 받기  
500 mg   견적 받기  

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 publication(s) in Google Scholar

Other Forms of L-Histidine-d5 hydrochloride hydrate:

L-Histidine-d5 hydrochloride hydrate Related Antibodies

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제품 설명

L-Histidine-d5 hydrochloride hydrate is the deuterium labeled L-Histidine hydrochloride hydrate (HY-W014423). L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable[1][2][3].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-Histidine-d5 hydrochloride hydrate Related Antibodies
분자량

214.66

화학식

C6H7D5ClN3O3
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

OC([C@](N)([2H])C([2H])([2H])C1=C([2H])N=C([2H])N1)=O.Cl.O
선적

Room temperature in continental US; may vary elsewhere.
보관

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

H2O : 125 mg/mL (582.32 mM; ultrasonic and adjust pH to 6 with NaOH)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6585 mL 23.2926 mL 46.5853 mL
5 mM 0.9317 mL 4.6585 mL 9.3171 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.6585 mL 23.2926 mL 46.5853 mL 116.4632 mL
5 mM 0.9317 mL 4.6585 mL 9.3171 mL 23.2926 mL
10 mM 0.4659 mL 2.3293 mL 4.6585 mL 11.6463 mL
15 mM 0.3106 mL 1.5528 mL 3.1057 mL 7.7642 mL
20 mM 0.2329 mL 1.1646 mL 2.3293 mL 5.8232 mL
25 mM 0.1863 mL 0.9317 mL 1.8634 mL 4.6585 mL
30 mM 0.1553 mL 0.7764 mL 1.5528 mL 3.8821 mL
40 mM 0.1165 mL 0.5823 mL 1.1646 mL 2.9116 mL
50 mM 0.0932 mL 0.4659 mL 0.9317 mL 2.3293 mL
60 mM 0.0776 mL 0.3882 mL 0.7764 mL 1.9411 mL
80 mM 0.0582 mL 0.2912 mL 0.5823 mL 1.4558 mL
100 mM 0.0466 mL 0.2329 mL 0.4659 mL 1.1646 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-Histidine-d5 hydrochloride hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-Histidine-d5 hydrochloride2483831-75-8H-His-OH-d5 hydrochlorideReactive Oxygen Species (ROS)Endogenous MetaboliteApoptosisIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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상품명:
L-Histidine-d5 hydrochloride hydrate
Cat. No.:
HY-W014423S4
수량:
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