Skatole-d3
Based on 1 Customer Validation
Skatole-d3 is the deuterium labeled Skatole. Skatole is produced by intestinal bacteria, regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.10%
- CAS. Nr.: 111399-60-1
- Formel: C9H6D3N
- Molecular Weight:134.19
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 111399-60-1
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Unlabeled Cas 83-34-1
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Appearance Solid
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Molecular Weight 134.19
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Formel C9H6D3N
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Color White to off-white
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SMILES
[2H]C(C1=CNC2=C1C=CC=C2)([2H])[2H]
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Synonyms
3-Methylindole-d3; 3-Methyl-1H-indole-d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 100 mg/mL (745.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Kurata K, et al. Skatole regulates intestinal epithelial cellular functions through activating aryl hydrocarbon receptors and p38. Biochem Biophys Res Commun. 2019 Mar 19;510(4):649-655. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.4521 mL | 37.2606 mL | 74.5212 mL | 186.3030 mL |
| 5 mM | 1.4904 mL | 7.4521 mL | 14.9042 mL | 37.2606 mL | |
| 10 mM | 0.7452 mL | 3.7261 mL | 7.4521 mL | 18.6303 mL | |
| 15 mM | 0.4968 mL | 2.4840 mL | 4.9681 mL | 12.4202 mL | |
| 20 mM | 0.3726 mL | 1.8630 mL | 3.7261 mL | 9.3151 mL | |
| 25 mM | 0.2981 mL | 1.4904 mL | 2.9808 mL | 7.4521 mL | |
| 30 mM | 0.2484 mL | 1.2420 mL | 2.4840 mL | 6.2101 mL | |
| 40 mM | 0.1863 mL | 0.9315 mL | 1.8630 mL | 4.6576 mL | |
| 50 mM | 0.1490 mL | 0.7452 mL | 1.4904 mL | 3.7261 mL | |
| 60 mM | 0.1242 mL | 0.6210 mL | 1.2420 mL | 3.1050 mL | |
| 80 mM | 0.0932 mL | 0.4658 mL | 0.9315 mL | 2.3288 mL | |
| 100 mM | 0.0745 mL | 0.3726 mL | 0.7452 mL | 1.8630 mL |
Skatole-d3 Related Classifications
HY-W007355S Related Classifications
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