Phenylglyoxylic acid-d5 sodium
Based on 1 Customer Validation
Phenylglyoxylic acid-d5 (Benzoylformic acid-d5) sodium is the deuterium labeled Phenylglyoxylic acid sodium (HY-W010255A). Phenylglyoxylic acid (Benzoylformic acid) is a metabolite of ethylbenzene and styrene (EB/S) and can be used as a biomarker of exposure to EB/S in human. Phenylglyoxylic acid can be used as drug intermediate for synthesis of antineoplastic compounds.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 2708283-39-8
- Formula: C8HD5NaO3
- Molecular Weight:178.15
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 2708283-39-8
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Unlabeled Cas 43165-51-1
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Appearance Solid
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Molecular Weight 178.15
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Formula C8HD5NaO3
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Color White to off-white
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SMILES
OC(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])=O)=O.[Na]
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Synonyms
Benzoylformic acid-d5sodium; Sodium phenylglyoxylate-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : ≥ 100 mg/mL (561.32 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Capella KM, et al. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012. Environ Res. 2019 Apr;171:101-110. [Content Brief]
[3]. Jiang W, et al., Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2020 Jan;94:103402. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.6132 mL | 28.0662 mL | 56.1325 mL | 140.3312 mL |
| 5 mM | 1.1226 mL | 5.6132 mL | 11.2265 mL | 28.0662 mL | |
| 10 mM | 0.5613 mL | 2.8066 mL | 5.6132 mL | 14.0331 mL | |
| 15 mM | 0.3742 mL | 1.8711 mL | 3.7422 mL | 9.3554 mL | |
| 20 mM | 0.2807 mL | 1.4033 mL | 2.8066 mL | 7.0166 mL | |
| 25 mM | 0.2245 mL | 1.1226 mL | 2.2453 mL | 5.6132 mL | |
| 30 mM | 0.1871 mL | 0.9355 mL | 1.8711 mL | 4.6777 mL | |
| 40 mM | 0.1403 mL | 0.7017 mL | 1.4033 mL | 3.5083 mL | |
| 50 mM | 0.1123 mL | 0.5613 mL | 1.1226 mL | 2.8066 mL | |
| 60 mM | 0.0936 mL | 0.4678 mL | 0.9355 mL | 2.3389 mL | |
| 80 mM | 0.0702 mL | 0.3508 mL | 0.7017 mL | 1.7541 mL | |
| 100 mM | 0.0561 mL | 0.2807 mL | 0.5613 mL | 1.4033 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Phenylglyoxylic acid-d5 sodium Related Classifications
HY-W010255AS Related Classifications
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