1. GPCR/G Protein
    Apoptosis
  2. Endothelin Receptor
    Apoptosis
  3. Macitentan D4

Macitentan D4 (Synonyms: ACT-064992 D4)

Cat. No.: HY-14184S
Handling Instructions

Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan is used for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

For research use only. We do not sell to patients.

Macitentan D4 Chemical Structure

Macitentan D4 Chemical Structure

CAS No. : 1258428-05-5

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Description

Macitentan D4 (ACT-064992 D4) is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan is used for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH)[1].

IC50 & Target

ETA/ETB[1]

Molecular Weight

592.30

Formula

C₁₉H₁₆D₄Br₂N₆O₄S

CAS No.

1258428-05-5

SMILES

O=S(NCCC)(NC1=NC=NC(OC([2H])([2H])C([2H])([2H])OC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Macitentan D4ACT-064992 D4Macitentan D 4Macitentan D-4Endothelin ReceptorApoptosisorallynon-peptideETAETBendothelinidiopathicpulmonaryfibrosisarterialhypertensionInhibitorinhibitorinhibit

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