Macitentan-d4
Based on 1 Customer Validation
Macitentan-d4 is a deuterium labeled Sulfamethoxazole. Macitentan is an orally active, non-peptide dual ETA and ETB (endothelin) receptor antagonist. Macitentan has the potential for idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 1258428-05-5
- Formula: C19H16D4Br2N6O4S
- Molecular Weight:592.30
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ETA |
ETB |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1258428-05-5
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Unlabeled Cas 441798-33-0
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Appearance Solid
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Molecular Weight 592.30
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Formula C19H16D4Br2N6O4S
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Color Off-white to light yellow
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SMILES
O=S(NCCC)(NC1=NC=NC(OC([2H])([2H])C([2H])([2H])OC2=NC=C(Br)C=N2)=C1C3=CC=C(Br)C=C3)=O
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Synonyms
ACT-064992-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 50 mg/mL (84.42 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6883 mL | 8.4417 mL | 16.8833 mL | 42.2083 mL |
| 5 mM | 0.3377 mL | 1.6883 mL | 3.3767 mL | 8.4417 mL | |
| 10 mM | 0.1688 mL | 0.8442 mL | 1.6883 mL | 4.2208 mL | |
| 15 mM | 0.1126 mL | 0.5628 mL | 1.1256 mL | 2.8139 mL | |
| 20 mM | 0.0844 mL | 0.4221 mL | 0.8442 mL | 2.1104 mL | |
| 25 mM | 0.0675 mL | 0.3377 mL | 0.6753 mL | 1.6883 mL | |
| 30 mM | 0.0563 mL | 0.2814 mL | 0.5628 mL | 1.4069 mL | |
| 40 mM | 0.0422 mL | 0.2110 mL | 0.4221 mL | 1.0552 mL | |
| 50 mM | 0.0338 mL | 0.1688 mL | 0.3377 mL | 0.8442 mL | |
| 60 mM | 0.0281 mL | 0.1407 mL | 0.2814 mL | 0.7035 mL | |
| 80 mM | 0.0211 mL | 0.1055 mL | 0.2110 mL | 0.5276 mL |
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