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  3. Biochemical Assay Reagents Isotope-Labeled Compounds
  4. Triacetonamine-d17

Triacetonamine-d17  (Synonyms: 2,2,6,6-Tetramethyl-4-piperidone-d17)

Cat. No.: HY-N1131S Purity: 99.72%
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Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats.

For research use only. We do not sell to patients.

Triacetonamine-d<sub>17</sub> Chemical Structure

Triacetonamine-d17 Chemical Structure

CAS No. : 52168-48-6

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1 mg USD 60 In-stock
5 mg USD 150 In-stock
10 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Triacetonamine-d17:

Triacetonamine-d17 Related Antibodies

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Description

Triacetonamine-d17 (2,2,6,6-Tetramethyl-4-piperidone-d17) is the deuterium labeled Triacetonamine. Triacetonamine has oral activity and can induce acute liver failure (ALF) in rats[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Triacetonamine-d17 Related Antibodies
Molecular Weight

172.34

Formula

C9D17NO
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C1(N([2H])C(C([2H])([2H])[2H])(C([2H])([2H])C(C1([2H])[2H])=O)C([2H])([2H])[2H])C([2H])([2H])[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (580.25 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Ethanol : 50 mg/mL (290.12 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8025 mL 29.0124 mL 58.0248 mL
5 mM 1.1605 mL 5.8025 mL 11.6050 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / DMSO 1 mM 5.8025 mL 29.0124 mL 58.0248 mL 145.0621 mL
5 mM 1.1605 mL 5.8025 mL 11.6050 mL 29.0124 mL
10 mM 0.5802 mL 2.9012 mL 5.8025 mL 14.5062 mL
15 mM 0.3868 mL 1.9342 mL 3.8683 mL 9.6708 mL
20 mM 0.2901 mL 1.4506 mL 2.9012 mL 7.2531 mL
25 mM 0.2321 mL 1.1605 mL 2.3210 mL 5.8025 mL
30 mM 0.1934 mL 0.9671 mL 1.9342 mL 4.8354 mL
40 mM 0.1451 mL 0.7253 mL 1.4506 mL 3.6266 mL
50 mM 0.1160 mL 0.5802 mL 1.1605 mL 2.9012 mL
60 mM 0.0967 mL 0.4835 mL 0.9671 mL 2.4177 mL
80 mM 0.0725 mL 0.3627 mL 0.7253 mL 1.8133 mL
100 mM 0.0580 mL 0.2901 mL 0.5802 mL 1.4506 mL
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Triacetonamine-d17 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triacetonamine-d1752168-48-62,2,6,6-Tetramethyl-4-piperidone-d17Biochemical Assay ReagentsIsotope-Labeled CompoundsInhibitorinhibitorinhibit

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