1. GPCR/G Protein
    Neuronal Signaling
  2. 5-HT Receptor
  3. Mirtazapine D3

Mirtazapine D3 (Synonyms: Org3770 D3; 6-Azamianserin D3)

Cat. No.: HY-B0352S Purity: 99.49%
Handling Instructions

Mirtazapine D3 (Org3770 D3; 6-Azamianserin D3) is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors.

For research use only. We do not sell to patients.

Mirtazapine D3 Chemical Structure

Mirtazapine D3 Chemical Structure

CAS No. : 1216678-68-0

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1 mg USD 120 In-stock
Estimated Time of Arrival: December 31
5 mg USD 450 In-stock
Estimated Time of Arrival: December 31
10 mg USD 770 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Mirtazapine D3 (Org3770 D3; 6-Azamianserin D3) is a deuterium labeled Mirtazapine. Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].

IC50 & Target

5-HT2 Receptor

 

5-HT3 Receptor

 

In Vivo

Mirtazapine (intraperitoneal injection; 10–50 mg/Kg; 14 days) treatment normalizes heart rate, breath rate, anxiety levels and eliminates the hopping behavior observed in MeCP2-null mice, leading to improved phenotypic score[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: MeCP2 null mice[2]
Dosage: 10-50 mg/Kg
Administration: Intraperitoneal injection; 10-50 mg/Kg; 14 days
Result: Restored the thickness of MeCP2-null mice somatosensory cortex, especially of layers II-III and VI.
Molecular Weight

268.37

Formula

C17H16D3N3

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
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