Nitrofurazone-13C,15N2
Based on 1 Customer Validation
Nitrofurazone-13C,15N2 (Nitrofural-13C,15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226). Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants. Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna.
For research use only. We do not sell to patients.
- Purity: 99.56%
- CAS No.: 1217220-85-3
- Formula: C513CH6N215N2O4
- Molecular Weight:201.12
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1217220-85-3
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Unlabeled Cas 59-87-0
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Appearance Solid
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Molecular Weight 201.12
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Formula C513CH6N215N2O4
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Color White to yellow
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SMILES
O=[13C]([15NH]/[15N]=C/C1=CC=C([N+]([O-])=O)O1)N
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Synonyms
Nitrofural-13C,15N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 155 mg/mL (770.68 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (558 KB)
- English - EN (558 KB)
- Français - FR (558 KB)
- Deutsch - DE (558 KB)
- Norwegian - NO (558 KB)
- Español - ES (558 KB)
- Swedish - SV (558 KB)
- Italian - IT (558 KB)
- Korean - KR (558 KB)
- Portuguese - PT (558 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Uroosa, et al. Effects of nitrofurazone on ecosystem function in marine environments: A case study on microbial fauna. Mar Pollut Bull. 2022 Nov;184:114216. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9722 mL | 24.8608 mL | 49.7216 mL | 124.3039 mL |
| 5 mM | 0.9944 mL | 4.9722 mL | 9.9443 mL | 24.8608 mL | |
| 10 mM | 0.4972 mL | 2.4861 mL | 4.9722 mL | 12.4304 mL | |
| 15 mM | 0.3315 mL | 1.6574 mL | 3.3148 mL | 8.2869 mL | |
| 20 mM | 0.2486 mL | 1.2430 mL | 2.4861 mL | 6.2152 mL | |
| 25 mM | 0.1989 mL | 0.9944 mL | 1.9889 mL | 4.9722 mL | |
| 30 mM | 0.1657 mL | 0.8287 mL | 1.6574 mL | 4.1435 mL | |
| 40 mM | 0.1243 mL | 0.6215 mL | 1.2430 mL | 3.1076 mL | |
| 50 mM | 0.0994 mL | 0.4972 mL | 0.9944 mL | 2.4861 mL | |
| 60 mM | 0.0829 mL | 0.4143 mL | 0.8287 mL | 2.0717 mL | |
| 80 mM | 0.0622 mL | 0.3108 mL | 0.6215 mL | 1.5538 mL | |
| 100 mM | 0.0497 mL | 0.2486 mL | 0.4972 mL | 1.2430 mL |