59-87-0
59-87-0
Chemical Structure
Nitrofurazone
Synonym(s): Nitrofural
- CAS No.: 59-87-0
- Formula:C6H6N4O4
- Molecular Weight:198.14
IUPAC Name: (E)-2-((5-nitrofuran-2-yl)methylene)hydrazine-1-carboxamide
InChIKey: IAIWVQXQOWNYOU-FPYGCLRLSA-N
SMILES: O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)N
Biological Activity: Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Nitrofurazone | 99.96% | Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria. | ||||||||||||||||||||
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Nitrofurazone (Standard) | ≥98% | Nitrofurazone (Standard) is the analytical standard of Nitrofurazone. This product is intended for research and analytical applications. Nitrofurazone (Nitrofural) is a broad spectrum antibiotic that has oral activity. Nitrofurazone is a nitro-aromatic drug. Nitrofurazone is active against both Gram-positive and Gram-negative bacteria. | ||||||||||||||||||||
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Nitrofurazone-13C,15N2 | 99.56% | Nitrofurazone-13C,15N2 (Nitrofural-13C,15N2) is the 13C and 15N labled Nitrofurazone (HY-B0226). Nitrofurazone is a potential antibiotic that can be used topically to treat wounds, burns, ulcers and skin infections to combat various microorganisms and to prepare surfactants. Nitrofurazone may affect the ecosystem function in Marine environment and affect the functional processes of epiphytic fauna. | ||||||||||||||||||||
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References
- [1]. Ryan A, et al. Activation of nitrofurazone by azoreductases: multiple activities in one enzyme. Sci Rep. 2011;1:63. [Content Brief]
- [2]. McCalla DR, et al. Mode of action of nitrofurazone. J Bacteriol. 1970 Dec;104(3):1126-34. [Content Brief]
- [3]. Tu Y, et al. Effect of nitrofurazone on bacterial RNA and ribosome synthesis and on the function of ribosomes. Chem Biol Interact. 1976 Jul;14(1-2):81-91. [Content Brief]
- [4]. Z Kari FW, et al. Toxicity and carcinogenicity of nitrofurazone in F344/N rats and B6C3F1 mice. Food Chem Toxicol. 1989 Feb;27(2):129-37. [Content Brief]
- [5]. Neal RA, et al. The activity of nitrofurazone and furazolidone against Leishmania donovani, L. major and L. enriettii in vitro and in vivo. Ann Trop Med Parasitol. 1988 Oct;82(5):453-6. [Content Brief]
