1-Methylimidazoleacetic acid-d3
Based on 1 Customer Validation
1-Methylimidazoleacetic acid (1-Methylimidazole-4-acetic acid)-d3 is deuterium labeled 1-Methylimidazoleacetic acid (HY-13936). 1-Methylimidazoleacetic acid is a Histamine (HY-B1204) metabolite. 1-Methylimidazoleacetic acid serves as a biomarker for the detection of mastocytosis.
For research use only. We do not sell to patients.
- Purity : 98.22%
- CAS No.: 122380-33-0
- Formula: C6H5D3N2O2
- Molecular Weight:143.16
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Storage:
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 122380-33-0
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Unlabeled CAS 2625-49-2
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Appearance Solid
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Molecular Weight 143.16
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Formula C6H5D3N2O2
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SMILES
O=C(O)CC1=CN(C([2H])([2H])[2H])C=N1
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Synonyms
1-Methylimidazole-4-acetic acid-d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 20 mg/mL (139.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.9852 mL | 34.9260 mL | 69.8519 mL | 174.6298 mL |
| 5 mM | 1.3970 mL | 6.9852 mL | 13.9704 mL | 34.9260 mL | |
| 10 mM | 0.6985 mL | 3.4926 mL | 6.9852 mL | 17.4630 mL | |
| 15 mM | 0.4657 mL | 2.3284 mL | 4.6568 mL | 11.6420 mL | |
| 20 mM | 0.3493 mL | 1.7463 mL | 3.4926 mL | 8.7315 mL | |
| 25 mM | 0.2794 mL | 1.3970 mL | 2.7941 mL | 6.9852 mL | |
| 30 mM | 0.2328 mL | 1.1642 mL | 2.3284 mL | 5.8210 mL | |
| 40 mM | 0.1746 mL | 0.8731 mL | 1.7463 mL | 4.3657 mL | |
| 50 mM | 0.1397 mL | 0.6985 mL | 1.3970 mL | 3.4926 mL | |
| 60 mM | 0.1164 mL | 0.5821 mL | 1.1642 mL | 2.9105 mL | |
| 80 mM | 0.0873 mL | 0.4366 mL | 0.8731 mL | 2.1829 mL | |
| 100 mM | 0.0699 mL | 0.3493 mL | 0.6985 mL | 1.7463 mL |
1-Methylimidazoleacetic acid-d3 Related Classifications
HY-13936S Related Classifications
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