Triclabendazole-13C,d3
Triclabendazole-13C,d3 is the 13C- and deuterium labeled Triclabendazole.
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- CAS. Nr.: 2938916-53-9
- Formel: C1313CH6D3Cl3N2OS
- Molecular Weight:363.67
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[52].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 2938916-53-9
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Unlabeled CAS 68786-66-3
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Molecular Weight 363.67
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Formel C1313CH6D3Cl3N2OS
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SMILES
ClC1=C(Cl)C(OC2=C(Cl)C=C3C(N=C(S[13C]([2H])([2H])[2H])N3)=C2)=CC=C1
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Synonyms
CGA89317-13C,d3
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [Content Brief]
[2]. Moll, L., et al., Resistance of Fasciola hepatica against triclabendazole in cattle and sheep in The netherlands. Vet Parasitol, 2000. 91(1-2): p. 153-8. [Content Brief]
[3]. Robinson, M.W., et al., Triclabendazole-resistant Fasciola hepatica: beta-tubulin and response to in vitro treatment with triclabendazole. Parasitology, 2002. 124(Pt 3): p. 325-38. [Content Brief]
[4]. Fairweather, I., Triclabendazole: new skills to unravel an old(ish) enigma. J Helminthol, 2005. 79(3): p. 227-34. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Triclabendazole-13C,d3 Related Classifications
HY-B0621S1 Related Classifications
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