p-Anisic acid-d4
Based on 1 Customer Validation
p-Anisic acid-d4 is the deuterium labeled p-Anisic acid. p-Anisic acid (4-Methoxybenzoic acid) is one of the isomers of anisic acid, with anti-bacterial and antiseptic properties.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 152404-46-1
- Formula: C8H4D4O3
- Molecular Weight:156.17
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 152404-46-1
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Unlabeled Cas 100-09-4
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Appearance Solid
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Molecular Weight 156.17
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Formula C8H4D4O3
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Color White to off-white
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SMILES
O=C(O)C1=C([2H])C([2H])=C(OC)C([2H])=C1[2H]
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Synonyms
4-Methoxybenzoic acid-d4; Draconic acid-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (320.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. DeWeerd K, et al. Metabolism of the 18O-methoxy substituent of 3-methoxybenzoic acid and other unlabeled methoxybenzoic acids by anaerobic bacteria. Appl Environ Microbiol. 1988 May;54(5):1237-42. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4033 mL | 32.0164 mL | 64.0328 mL | 160.0820 mL |
| 5 mM | 1.2807 mL | 6.4033 mL | 12.8066 mL | 32.0164 mL | |
| 10 mM | 0.6403 mL | 3.2016 mL | 6.4033 mL | 16.0082 mL | |
| 15 mM | 0.4269 mL | 2.1344 mL | 4.2689 mL | 10.6721 mL | |
| 20 mM | 0.3202 mL | 1.6008 mL | 3.2016 mL | 8.0041 mL | |
| 25 mM | 0.2561 mL | 1.2807 mL | 2.5613 mL | 6.4033 mL | |
| 30 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3361 mL | |
| 40 mM | 0.1601 mL | 0.8004 mL | 1.6008 mL | 4.0020 mL | |
| 50 mM | 0.1281 mL | 0.6403 mL | 1.2807 mL | 3.2016 mL | |
| 60 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 80 mM | 0.0800 mL | 0.4002 mL | 0.8004 mL | 2.0010 mL | |
| 100 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6008 mL |
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