1. Immunology/Inflammation
    Autophagy
  2. COX
    Autophagy
  3. Indomethacin-D4

Indomethacin-D4 (Synonyms: Indometacin-D4)

Cat. No.: HY-14397S
Handling Instructions

Indomethacin-D4 (Indometacin-D4) is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.

For research use only. We do not sell to patients.

Indomethacin-D4 Chemical Structure

Indomethacin-D4 Chemical Structure

CAS No. : 87377-08-0

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Description

Indomethacin-D4 (Indometacin-D4) is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells[1].

IC50 & Target[1]

Human COX-1

18 nM (IC50, in CHO cells)

Human COX-2

26 nM (IC50, in CHO cells)

Molecular Weight

361.81

Formula

C₁₉H₁₂D₄ClNO₄

CAS No.

87377-08-0

SMILES

O=C(O)CC1=C(C)N(C(C2=C([2H])C([2H])=C(Cl)C([2H])=C2[2H])=O)C3=C1C=C(OC)C=C3

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Indomethacin-D4Indometacin-D4COXAutophagyCyclooxygenaseInhibitorinhibitorinhibit

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