Salbutamol-d9
Based on 1 Customer Validation
Salbutamol-d9 (Albuterol-d9) is the deuterium labeled Salbutamol (HY-B1037). Salbutamol (Albuterol) is an orally active short-acting β2-adrenergic receptor agonist. Salbutamol promotes tumorigenesis in gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol can relax bronchial smooth muscle and is used to study bronchospasm induced by asthma and chronic obstructive pulmonary disease.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 1173021-73-2
- Formula: C13H12D9NO3
- Molecular Weight:248.37
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Adrenergic Receptor Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1173021-73-2
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Unlabeled Cas 18559-94-9
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Appearance Solid
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Molecular Weight 248.37
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Formula C13H12D9NO3
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Color White to off-white
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SMILES
OC(CNC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])C1=CC=C(O)C(CO)=C1
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Synonyms
Albuterol-d9; AH-3365-d9
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (402.63 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412. [Content Brief]
[2]. Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0263 mL | 20.1313 mL | 40.2625 mL | 100.6563 mL |
| 5 mM | 0.8053 mL | 4.0263 mL | 8.0525 mL | 20.1313 mL | |
| 10 mM | 0.4026 mL | 2.0131 mL | 4.0263 mL | 10.0656 mL | |
| 15 mM | 0.2684 mL | 1.3421 mL | 2.6842 mL | 6.7104 mL | |
| 20 mM | 0.2013 mL | 1.0066 mL | 2.0131 mL | 5.0328 mL | |
| 25 mM | 0.1611 mL | 0.8053 mL | 1.6105 mL | 4.0263 mL | |
| 30 mM | 0.1342 mL | 0.6710 mL | 1.3421 mL | 3.3552 mL | |
| 40 mM | 0.1007 mL | 0.5033 mL | 1.0066 mL | 2.5164 mL | |
| 50 mM | 0.0805 mL | 0.4026 mL | 0.8053 mL | 2.0131 mL | |
| 60 mM | 0.0671 mL | 0.3355 mL | 0.6710 mL | 1.6776 mL | |
| 80 mM | 0.0503 mL | 0.2516 mL | 0.5033 mL | 1.2582 mL | |
| 100 mM | 0.0403 mL | 0.2013 mL | 0.4026 mL | 1.0066 mL |
Salbutamol-d9 Related Classifications
HY-B1037S2 Related Classifications
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