1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Glutaric acid-d6

Glutaric acid-d6 

Cat. No.: HY-W008820S Purity: ≥98.0%
Handling Instructions

Glutaric acid-d6 is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I.

For research use only. We do not sell to patients.

Glutaric acid-d6 Chemical Structure

Glutaric acid-d6 Chemical Structure

CAS No. : 154184-99-3

Size Price Stock Quantity
10 mg USD 150 In-stock
Estimated Time of Arrival: December 31
25 mg USD 235 In-stock
Estimated Time of Arrival: December 31
50 mg USD 325 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Glutaric acid-d6 is the deuterium labeled Glutaric acid. Glutaric acid is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

138.15

Formula

C5H2D6O4

CAS No.
SMILES

O=C(O)C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1809.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.2385 mL 36.1925 mL 72.3851 mL
5 mM 1.4477 mL 7.2385 mL 14.4770 mL
10 mM 0.7239 mL 3.6193 mL 7.2385 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (15.06 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (15.06 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (15.06 mM); Clear solution

*All of the co-solvents are available by MCE.
References
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Product Name:
Glutaric acid-d6
Cat. No.:
HY-W008820S
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