Azelaic acid-d14
Based on 1 Customer Validation
Azelaic acid-d14 is the deuterium labeled Azelaic acid. Azelaic acid is an organic compound produced by the ozonolysis of oleic acid;component of a number of hair and skin conditioners.
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- Reinheit : 99.86%
- CAS. Nr.: 119176-67-9
- Formel: C9H2D14O4
- Molecular Weight:202.31
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Speicherung:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Anwendung
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 119176-67-9
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Unlabeled CAS 123-99-9
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Appearance Solid
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Molecular Weight 202.31
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Formel C9H2D14O4
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Color White to yellow
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SMILES
OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(O)=O)=O
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Synonyms
Nonanedioic acid-d14
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (494.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Jung HW, et al. Priming in systemic plant immunity. Science. 2009 Apr 3;324(5923):89-91. [Content Brief]
[3]. Liu RH, et al. Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials. Arch Dermatol. 2006 Aug142(8):1047-52. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.9429 mL | 24.7145 mL | 49.4291 mL | 123.5727 mL |
| 5 mM | 0.9886 mL | 4.9429 mL | 9.8858 mL | 24.7145 mL | |
| 10 mM | 0.4943 mL | 2.4715 mL | 4.9429 mL | 12.3573 mL | |
| 15 mM | 0.3295 mL | 1.6476 mL | 3.2953 mL | 8.2382 mL | |
| 20 mM | 0.2471 mL | 1.2357 mL | 2.4715 mL | 6.1786 mL | |
| 25 mM | 0.1977 mL | 0.9886 mL | 1.9772 mL | 4.9429 mL | |
| 30 mM | 0.1648 mL | 0.8238 mL | 1.6476 mL | 4.1191 mL | |
| 40 mM | 0.1236 mL | 0.6179 mL | 1.2357 mL | 3.0893 mL | |
| 50 mM | 0.0989 mL | 0.4943 mL | 0.9886 mL | 2.4715 mL | |
| 60 mM | 0.0824 mL | 0.4119 mL | 0.8238 mL | 2.0595 mL | |
| 80 mM | 0.0618 mL | 0.3089 mL | 0.6179 mL | 1.5447 mL | |
| 100 mM | 0.0494 mL | 0.2471 mL | 0.4943 mL | 1.2357 mL |
Azelaic acid-d14 Related Classifications
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