1. Others Membrane Transporter/Ion Channel Autophagy Apoptosis
  2. Isotope-Labeled Compounds Proton Pump Autophagy Apoptosis
  3. Pantoprazole-d6

Pantoprazole-d6  (Synonyms: BY1023-d6; SKF96022-d6)

Cat. No.: HY-17507S
Handling Instructions

Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].

For research use only. We do not sell to patients.

Pantoprazole-d<sub>6</sub> Chemical Structure

Pantoprazole-d6 Chemical Structure

CAS No. : 922727-65-9

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Based on 1 publication(s) in Google Scholar

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Description

Pantoprazole-d6 is deuterium labeled Pantoprazole. Pantoprazole (BY10232) is an orally active and potent proton pump inhibitor (PPI)[1]. Pantoprazole, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole significantly increased tumor growth delay combined with Doxorubicin (HY-15142)[3][4].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

389.41

Formula

C16H9D6F2N3O4S

CAS No.
Unlabeled CAS

102625-70-7

SMILES

O=S(C1=NC2=CC=C(OC(F)F)C=C2N1)CC3=NC=CC(OC([2H])([2H])[2H])=C3OC([2H])([2H])[2H]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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